DAWN trial: solution or problem?

Key point: To assess the mean score for disability on the utility-weighted modified Rankin scale and the rate of functional independence (mRS≤2) at 90 days. The main results of the “magnificent seven” (MR-CLEAN, ESCAPE, EXTEND-IA, SWIFT PRIME, REVASCAT, THRACE, THERAPY) regarding stroke therapy showed that endovascular thrombectomy had a clinical benefit when it was performed within Read more about DAWN trial: solution or problem?[…]

Clot friction variation with fibrin content; implications for resistance to thrombectomy.

Gunning GM1, McArdle K1, Mirza M1, Duffy S1,2, Gilvarry M1, Brouwer PA3. Abstract BACKGROUND: Despite significant advancements in the procedural efficacy of mechanical thrombectomy in patients with ischemic stroke in recent years, there still remains a portion of the population that does not achieve good recanalization. The reasons for this may be varied. We hypothesized Read more about Clot friction variation with fibrin content; implications for resistance to thrombectomy.[…]

Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials

Goyal M1, Menon BK1, van Zwam WH2, Dippel DW3, Mitchell PJ4, Demchuk AM1, Dávalos A5, Majoie CB6, van der Lugt A3, de Miquel MA7, Donnan GA8, Roos YB6, Bonafe A9, Jahan R10, Diener HC11, van den Berg LA6, Levy EI12, Berkhemer OA6, Pereira VM13, Rempel J14, Millán M15, Davis SM16, Roy D17, Thornton J18, Román Read more about Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials[…]

Training Guidelines for Endovascular Ischemic Stroke Intervention: An International Multi-Society Consensus Document.

Lavine SD, Cockroft K, Hoh B, Bambakidis N, Khalessi AA, Woo H, Riina H, Siddiqui A, Hirsch JA, Chong W, Rice H, Wenderoth J, Mitchell P, Coulthard A, Signh TJ, Phatorous C, Khangure M, Klurfan P, terBrugge K, Iancu D, Gunnarsson T, Jansen O, Muto M, Szikora I, Pierot L, Brouwer P, Gralla J, Renowden Read more about Training Guidelines for Endovascular Ischemic Stroke Intervention: An International Multi-Society Consensus Document.[…]

Direct Mechanical Intervention Versus Combined Intravenous and Mechanical Intervention in Large Artery Anterior Circulation Stroke: A Matched-Pairs Analysis.

Anne Broeg-Morvay, Pasquale Mordasini, Corrado Bernasconi, Monika Bühlmann, Frauke Pult, Marcel Arnold, Gerhard Schroth, Simon Jung, Heinrich P. Mattle, Jan Gralla, Urs Fischer Abstract BACKGROUND AND PURPOSE: Five randomized controlled trials have consistently shown that mechanical thrombectomy (MT) in addition to best medical treatment (±intravenous tissue-type plasminogen activator) improves outcome after acute ischemic stroke in Read more about Direct Mechanical Intervention Versus Combined Intravenous and Mechanical Intervention in Large Artery Anterior Circulation Stroke: A Matched-Pairs Analysis.[…]