DAWN trial: solution or problem?

Key point: To assess the mean score for disability on the utility-weighted modified Rankin scale and the rate of functional independence (mRS≤2) at 90 days. The main results of the “magnificent seven” (MR-CLEAN, ESCAPE, EXTEND-IA, SWIFT PRIME, REVASCAT, THRACE, THERAPY) regarding stroke therapy showed that endovascular thrombectomy had a clinical benefit when it was performed within Read more about DAWN trial: solution or problem?[…]

Anesthesia Technique and Outcomes of Mechanical Thrombectomy in Patients With Acute Ischemic Stroke.

Bekelis K1, Missios S2, MacKenzie TA2, Tjoumakaris S2, Jabbour P2.   Pubmed BACKGROUND AND PURPOSE: The impact of anesthesia technique on the outcomes of mechanical thrombectomy for acute ischemic stroke remains an issue of debate. We investigated the association of general anesthesia with outcomes in patients undergoing mechanicalthrombectomy for ischemic stroke. METHODS: We performed a Read more about Anesthesia Technique and Outcomes of Mechanical Thrombectomy in Patients With Acute Ischemic Stroke.[…]

Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials

Goyal M1, Menon BK1, van Zwam WH2, Dippel DW3, Mitchell PJ4, Demchuk AM1, Dávalos A5, Majoie CB6, van der Lugt A3, de Miquel MA7, Donnan GA8, Roos YB6, Bonafe A9, Jahan R10, Diener HC11, van den Berg LA6, Levy EI12, Berkhemer OA6, Pereira VM13, Rempel J14, Millán M15, Davis SM16, Roy D17, Thornton J18, Román Read more about Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials[…]

Direct Mechanical Intervention Versus Combined Intravenous and Mechanical Intervention in Large Artery Anterior Circulation Stroke: A Matched-Pairs Analysis.

Anne Broeg-Morvay, Pasquale Mordasini, Corrado Bernasconi, Monika Bühlmann, Frauke Pult, Marcel Arnold, Gerhard Schroth, Simon Jung, Heinrich P. Mattle, Jan Gralla, Urs Fischer Abstract BACKGROUND AND PURPOSE: Five randomized controlled trials have consistently shown that mechanical thrombectomy (MT) in addition to best medical treatment (±intravenous tissue-type plasminogen activator) improves outcome after acute ischemic stroke in Read more about Direct Mechanical Intervention Versus Combined Intravenous and Mechanical Intervention in Large Artery Anterior Circulation Stroke: A Matched-Pairs Analysis.[…]